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Major causes of infertility in women

Here are the major causes of infertility in women:


🧬 1. Ovulation Disorders

When eggs are not released regularly from the ovaries.

  • Polycystic Ovary Syndrome (PCOS)
  • Thyroid problems (hypo/hyperthyroidism)
  • Premature ovarian failure
  • Hyperprolactinemia (high prolactin levels)

🧫 2. Tubal Factors

Blocked or damaged fallopian tubes prevent sperm from reaching the egg.

  • Pelvic inflammatory disease (PID)
  • Tuberculosis
  • Previous ectopic pregnancy
  • Endometriosis

🏥 3. Uterine or Cervical Issues

Problems in the uterus or cervix interfere with implantation or sperm movement.

  • Fibroids
  • Polyps
  • Uterine septum or adhesions (Asherman’s syndrome)
  • Cervical stenosis or hostile cervical mucus

🩺 4. Endometriosis

When uterine lining tissue grows outside the uterus, causing inflammation and damage to pelvic organs.


⚖️ 5. Age-related Factors

Fertility declines with age, especially after 35 years, due to reduced egg quality and quantity.


💊 6. Hormonal Imbalances

Irregular levels of hormones like FSH, LH, estrogen, progesterone affect ovulation and menstruation.


⚠️ 7. Lifestyle Factors

  • Obesity or being underweight
  • Smoking or alcohol
  • Stress
  • Poor diet
  • Excessive exercise

🧬 8. Genetic or Chromosomal Conditions

  • Turner syndrome
  • Fragile X syndrome
  • Other inherited reproductive disorders

🧪 9. Unexplained Infertility

In 10–20% of cases, no exact cause is found even after tests.

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